Aceclofenac is an orally administered phenylacetic acid derivative with effects on a variety of inflammatory mediators. It is an effective analgesic and anti- inflammatory agent with a good tolerability profile. Through it’s analgesic and anti-inflammatory properties, Aceclofenac provides symptomatic relief in a variety of painful conditions. Aceclofenac has been shown to exert effects on a variety of mediators of inflammation. The drug inhibits synthesis of the inflammatory cytokines, prostaglandins and interleukins.
Aceclofenac is rapidly and completely absorbed after oral administration. Peak plasma concentration are reached in 1-3 hours after an oral dose. The drug is highly protein bound (>99%). Aceclofenac is metabolized to a major metabolite, 4-hydroxyaceclofenac and to a number of other metabolites including 5-hydroxyaceclofenac and diclofenac. These other metabolites account for the fate of approximately 20% of each dose of Aceclofenac. The plasma elimination half life of Aceclofenac is approximately 4 hours.
Belongs to a group of drug known as Non steroidal anti inflammatory drug(NSAID), although it itself has no anti – inflammatory activity Paracetamol is a clinically proven analgesic / antipyretic.
Paracetamol provides fast, effective, temporary relief of fever and discomfort due to cold and ‘flu’. It is also widely used to provide relief of pain and discomfort due to headache, muscle aches, sprains and over exertion.
- Fever, Bodyache, Arthritic pain
- Low back pain
- Dental pain
- Dysmenorrhoea, Episiotomy
- Post operative pain
Dosage and Administration
One tablet twice daily
- Hypersensitivity to Paracetamol
- Hepatic failure since Paracetamol is metabolized in liver and can aggravate hepatic failure
Usage in pregnancy and lactation
The drug is not recommended in pregnant or breast feeding women.
Blister pack of 10 tabs.10 Blisters in a box